Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis

Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis

Pathological and clinical studies implicate antibody-dependent mechanisms in the immunopathogenesis of multiple sclerosis. We tested this hypothesis directly by investigating the ability of patient-derived immunoglobulins to mediate demyelination and axonal injury in vitro. Using a myelinating culture system, we developed a sensitive and reproducible bioassay to detect and quantify these effect...

Effect of TRX Suspension Training on Functional Balance in Patients with Multiple Sclerosis

Introduction: Many people with multiple sclerosis (MS) experience difficulty with balance and walking, which can make daily activities difficult. Recent studies in rehabilitation procedures emphasize on functional suspension training using body weight resistance against gravity by unstable tools and equipment that are similar to daily activities. Therefore, the purpose of this study was to dete...

Psychological Changes in Patients With Multiple Sclerosis

Introduction: Multiple Sclerosis (MS) as a stressful event, despite causing negative psychological changes, may lead to positive ones as well. Objective: This study was mainly conducted to examine the implications of posttraumatic growth and demoralization and also to determine the relationship between them in patients with MS. Materials and Methods: This was a cross-sectional study, in which...

evaluation of fat atrophy in patients with dermis fat graft of orbit by ct-scan

چکیده ندارد.

Autoantibody Profiling in Multiple Sclerosis